Genetic Variants in Nuclear-Encoded Mitochondrial Genes Influence AIDS Progression

BACKGROUND: The human mitochondrial genome includes only 13 coding genes while nuclear-encoded genes account for 99% of proteins responsible for mitochondrial morphology, redox regulation, and energetics. Mitochondrial pathogenesis occurs in HIV patients and genetically, mitochondrial DNA haplogroup...

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Detalhes bibliográficos
Main Authors: Hendrickson, Sher L., Lautenberger, James A., Chinn, Leslie Wei, Malasky, Michael, Sezgin, Efe, Kingsley, Lawrence A., Goedert, James J., Kirk, Gregory D., Gomperts, Edward D., Buchbinder, Susan P., Troyer, Jennifer L., O'Brien, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943476/
https://ncbi.nlm.nih.gov/pubmed/20877624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012862
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