A point mutation in gp91-phox of cytochrome b558 of the human NADPH oxidase leading to defective translocation of the cytosolic proteins p47-phox and p67-phox.

The superoxide-forming NADPH oxidase of human phagocytes is composed of membrane-bound and cytosolic proteins which, upon cell activation, assemble on the plasma membrane to form the active enzyme. Patients suffering from chronic granulomatous disease (CGD) are defective in one of the following comp...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Leusen, J H, de Boer, M, Bolscher, B G, Hilarius, P M, Weening, R S, Ochs, H D, Roos, D, Verhoeven, A J
Médium: Artigo
Jazyk:Inglês
Vydáno: 1994
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC294341/
https://ncbi.nlm.nih.gov/pubmed/8182143
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky