A point mutation in gp91-phox of cytochrome b558 of the human NADPH oxidase leading to defective translocation of the cytosolic proteins p47-phox and p67-phox.

Ítems similars

• Interactions between cytosolic components of the NADPH oxidase: p40phox interacts with both p67phox and p47phox.
  per: Wientjes, F B, et al.
  Publicat: (1996)
• 156Pro-->Gln substitution in the light chain of cytochrome b558 of the human NADPH oxidase (p22-phox) leads to defective translocation of the cytosolic proteins p47-phox and p67-phox
  Publicat: (1994)
• p40(phox) Participates in the activation of NADPH oxidase by increasing the affinity of p47(phox) for flavocytochrome b(558).
  per: Cross, A R
  Publicat: (2000)
• Neutrophil nicotinamide adenine dinucleotide phosphate oxidase assembly. Translocation of p47-phox and p67-phox requires interaction between p47-phox and cytochrome b558.
  per: Heyworth, P G, et al.
  Publicat: (1991)
• Cytochrome b558-negative, autosomal recessive chronic granulomatous disease: two new mutations in the cytochrome b558 light chain of the NADPH oxidase (p22-phox).
  per: de Boer, M, et al.
  Publicat: (1992)