Nucleotide Release Provides a Mechanism for Airway Surface Liquid Homeostasis

Nucleotides within the airway surface liquid (ASL) regulate airway epithelial ion transport rates by Ca(2+)- and protein kinase C-dependent mechanisms via activation of specific P2Y receptors. Extracellular adenine nucleotides also serve as precursors for adenosine, which promotes cyclic AMP-mediate...

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Bibliografiske detaljer
Main Authors: Lazarowski, Eduardo R., Tarran, Robert, Grubb, Barbara R., van Heusden, Catharina A., Okada, Seiko, Boucher, Richard C.
Format: Artigo
Sprog:Inglês
Udgivet: 2004
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943374/
https://ncbi.nlm.nih.gov/pubmed/15210701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M405367200
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