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How to Design an Opioid Drug That Causes Reduced Tolerance and Dependence

Mu opioid receptor (MOR) agonists such as morphine are extremely effective treatments for acute pain. In the setting of chronic pain, however, their long-term utility is limited by the development of tolerance and physical dependence. Drug companies have tried to overcome these problems by simply “d...

詳細記述

保存先:
書誌詳細
主要な著者: Berger, Amy Chang, Whistler, Jennifer L.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943346/
https://ncbi.nlm.nih.gov/pubmed/20437553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.22002
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