Impaired Binding of the Age-related Macular Degeneration-associated Complement Factor H 402H Allotype to Bruch's Membrane in Human Retina

Age-related macular degeneration (AMD) is the predominant cause of blindness in the industrialized world where destruction of the macula, i.e. the central region of the retina, results in loss of vision. AMD is preceded by the formation of deposits in the macula, which accumulate between the Bruch&#...

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Bibliografske podrobnosti
Main Authors: Clark, Simon J., Perveen, Rahat, Hakobyan, Svetlana, Morgan, B. Paul, Sim, Robert B., Bishop, Paul N., Day, Anthony J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2010
Teme:
Glycobiology and Extracellular Matrices
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943316/
https://ncbi.nlm.nih.gov/pubmed/20660596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.103986
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