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Adenosine A(2A) Receptor Signaling and G(olf) Assembly Show a Specific Requirement for the γ(7) Subtype in the Striatum
The adenosine A(2A) receptor (A(2A)R) is increasingly recognized as a novel therapeutic target in Parkinson disease. In striatopallidal neurons, the G-protein α(olf) subtype is required to couple this receptor to adenylyl cyclase activation. It is now well established that the βγ dimer also performs...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2943273/ https://ncbi.nlm.nih.gov/pubmed/20639202 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.142620 |
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