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Expression of the mouse corticotropin-releasing hormone gene in vivo and targeted inactivation in embryonic stem cells.

Corticotropin-releasing hormone (CRH), one of the primary regulators of the hypothalamic-pituitary-adrenal (HPA) axis, exhibits abnormal regulation in pathologic states such as depression and anorexia nervosa. Analysis of the role of CRH in regulation of the HPA axis would be facilitated by the crea...

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Pubblicato in:J Clin Invest
Autori principali: Muglia, L J, Jenkins, N A, Gilbert, D J, Copeland, N G, Majzoub, J A
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1994
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294325/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8182138/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117201
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