Expression of the mouse corticotropin-releasing hormone gene in vivo and targeted inactivation in embryonic stem cells.

Corticotropin-releasing hormone (CRH), one of the primary regulators of the hypothalamic-pituitary-adrenal (HPA) axis, exhibits abnormal regulation in pathologic states such as depression and anorexia nervosa. Analysis of the role of CRH in regulation of the HPA axis would be facilitated by the crea...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Muglia, L J, Jenkins, N A, Gilbert, D J, Copeland, N G, Majzoub, J A
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1994
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294325/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8182138/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117201
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