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Defects in Mitochondrial Axonal Transport and Membrane Potential without Increased Reactive Oxygen Species Production in a Drosophila Model of Friedreich Ataxia
Friedreich ataxia, a neurodegenerative disorder resulting from frataxin deficiency, is thought to involve progressive cellular damage from oxidative stress. In Drosophila larvae with reduced frataxin expression (DfhIR), we evaluated possible mechanisms of cellular neuropathology by quantifying mitoc...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2943153/ https://ncbi.nlm.nih.gov/pubmed/20739558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0529-10.2010 |
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