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MULTICOLOR MONITORING OF DYSREGULATED PROTEIN KINASES IN CHRONIC MYELOGENOUS LEUKEMIA

The Bcr-Abl and Lyn protein tyrosine kinases have been separately linked to the emergence of imatinib resistance in patients with chronic myelogenous leukemia. We have developed fluorescent sensors for these kinases that are enzymatically and photophysically distinct, allowing us to simultaneously,...

詳細記述

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書誌詳細
主要な著者: Wang, Qunzhao, Zimmerman, Eric I., Toutchkine, Alexei, Martin, Timothy D., Graves, Lee M., Lawrence, David S.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943031/
https://ncbi.nlm.nih.gov/pubmed/20583816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb100099h
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