Interleukin-1 receptor antagonist decreases bone loss and bone resorption in ovariectomized rats.

Interleukin-1 (IL-1), a cytokine produced by bone marrow cells and bone cells, has been implicated in the pathogenesis of postmenopausal osteoporosis because of its potent stimulatory effects on bone resorption in vitro and in vivo. To investigate whether IL-1 plays a direct causal role in post ovar...

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Main Authors: Kimble, R B, Vannice, J L, Bloedow, D C, Thompson, R C, Hopfer, W, Kung, V T, Brownfield, C, Pacifici, R
Formato: Artigo
Idioma:Inglês
Publicado: 1994
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC294303/
https://ncbi.nlm.nih.gov/pubmed/8182127
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