Evidence for role of cytosolic free calcium in hypoxia-induced proximal tubule injury.

The role of cytosolic free Ca2+ ([Ca2+]i) in hypoxic injury was investigated in rat proximal tubules. [Ca2+]i was measured using fura-2 and cell injury was estimated with propidium iodide (PI) in individual tubules using video imaging fluorescence microscopy. [Ca2+]i increased from approximately 170...

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Pubblicato in:	J Clin Invest
Autori principali:	Kribben, A, Wieder, E D, Wetzels, J F, Yu, L, Gengaro, P E, Burke, T J, Schrier, R W
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1994
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294299/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8182125/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117183
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