An epoxygenase metabolite of arachidonic acid mediates angiotensin II-induced rises in cytosolic calcium in rabbit proximal tubule epithelial cells.

Previous studies from this and other laboratories have shown that angiotensin II (AII) induces [Ca2+]i transients in proximal tubular epithelium independent of phospholipase C. AII also stimulates formation of 5,6-epoxyeicosatrienoic acid (5,6-EET) from arachidonic acid by a cytochrome P450 epoxygen...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Madhun, Z T, Goldthwait, D A, McKay, D, Hopfer, U, Douglas, J G
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295359/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1650793/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115325
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