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Maintenance of duplicate genes and their functional redundancy by reduced expression

Although evolutionary theories predict functional divergence between duplicate genes, many old duplicates still maintain a high degree of functional similarity and are synthetically lethal or sick, an observation that has puzzled many geneticists. We propose that expression reduction, a special type...

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Detalhes bibliográficos
Main Authors: Qian, Wenfeng, Liao, Ben-Yang, Chang, Andrew Y.-F., Zhang, Jianzhi
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2942974/
https://ncbi.nlm.nih.gov/pubmed/20708291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2010.07.002
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