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Enhanced antimicrobial activity of engineered human lysozyme

Lysozymes contain a disproportionately large fraction of cationic residues, and are thereby attracted towards the negatively charged surface of bacterial targets. Importantly, this conserved biophysical property may inhibit lysozyme antibacterial function during acute and chronic infections. A mouse...

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Detalhes bibliográficos
Main Authors: Scanlon, Thomas C., Teneback, Charlotte C., Gill, Avinash, Bement, Jenna L., Weiner, Joshua A., Lamppa, John W., Leclair, Laurie W., Griswold, Karl E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2942966/
https://ncbi.nlm.nih.gov/pubmed/20604527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb1001119
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