Bioengineered Lysozyme Reduces Bacterial Burden and Inflammation in a Murine Model of Mucoid Pseudomonas aeruginosa Lung Infection

The spread of drug-resistant bacterial pathogens is a growing global concern and has prompted an effort to explore potential adjuvant and alternative therapies derived from nature's repertoire of bactericidal proteins and peptides. In humans, the airway surface liquid layer is a rich source of...

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Bibliographic Details
Main Authors: Teneback, Charlotte C., Scanlon, Thomas C., Wargo, Matthew J., Bement, Jenna L., Griswold, Karl E., Leclair, Laurie W.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
Subjects:
Experimental Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811238/
https://ncbi.nlm.nih.gov/pubmed/23979752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00500-13
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