Chromium genotoxicity: a double-edged sword

Certain forms of hexavalent chromium [Cr(VI)] are known respiratory carcinogens that induce a broad spectrum of DNA damage. Cr(VI)-carcinogenesis may be initiated or promoted through several mechanistic processes including, the intracellular metabolic reduction of Cr(VI) producing chromium species c...

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Bibliographic Details
Main Authors: Nickens, Kristen P., Patierno, Steven R., Ceryak, Susan
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2942955/
https://ncbi.nlm.nih.gov/pubmed/20430016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2010.04.018
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