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Minozac Treatment Prevents Increased Seizure Susceptibility in a Mouse “Two-Hit” Model of Closed Skull Traumatic Brain Injury and Electroconvulsive Shock-Induced Seizures

The mechanisms linking traumatic brain injury (TBI) to post-traumatic epilepsy (PTE) are not known and no therapy for prevention of PTE is available. We used a mouse closed-skull midline impact model to test the hypotheses that TBI increases susceptibility to seizures in a “two-hit” injury model, an...

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Detalhes bibliográficos
Main Authors: Chrzaszcz, MaryAnn, Venkatesan, Charu, Dragisic, Tina, Watterson, D. Martin, Wainwright, Mark S.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2942875/
https://ncbi.nlm.nih.gov/pubmed/20486807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2009.1227
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