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Lipid Peroxidation-Derived Reactive Aldehydes Directly and Differentially Impair Spinal Cord and Brain Mitochondrial Function

Mitochondrial bioenergetic dysfunction in traumatic spinal cord and brain injury is associated with post-traumatic free radical–mediated oxidative damage to proteins and lipids. Lipid peroxidation by-products, such as 4-hydroxy-2-nonenal and acrolein, can form adducts with proteins and exacerbate th...

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Detalhes bibliográficos
Main Authors: Vaishnav, Radhika A., Singh, Indrapal N., Miller, Darren M., Hall, Edward D.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2942874/
https://ncbi.nlm.nih.gov/pubmed/20392143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2009.1172
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