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Inhibition of class II histone deacetylases in the spinal cord attenuates inflammatory hyperalgesia

BACKGROUND: Several classes of histone deacetylases (HDACs) are expressed in the spinal cord that is a critical structure of the nociceptive pathway. HDAC-regulated histone acetylation is an important component of chromatin remodeling leading to epigenetic regulation of gene transcription. To unders...

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Detalhes bibliográficos
Main Authors: Bai, Guang, Wei, Dong, Zou, Shiping, Ren, Ke, Dubner, Ronald
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2942827/
https://ncbi.nlm.nih.gov/pubmed/20822541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-6-51
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