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Stimulation of the P2X(7) receptor kills rat retinal ganglion cells in vivo

The P2X(7) receptor is associated with the death of many cell types, and growing evidence supports its presence on neurons. Activation of the P2X(7) receptor on isolated retinal ganglion cells increases intracellular calcium levels and can kill the cells. Within the intact eye, however, glia and oth...

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Detalhes bibliográficos
Main Authors: Hu, Huiling, Lu, Wennan, Zhang, Mei, Zhang, Xiulan, Argall, Arthur J., Patel, Shaun, Lee, Ga Eun, Kim, Yong-Chul, Jacobson, Kenneth A., Laties, Alan M., Mitchell, Claire H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941978/
https://ncbi.nlm.nih.gov/pubmed/20599962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2010.06.017
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