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Notch and EGFR pathway interaction regulates neural stem cell number and self-renewal

Specialized cellular microenvironments, or “niches,” modulate stem cell properties, including cell number, self-renewal and fate decisions1,2. In the adult brain, niches that maintain a source of neural stem cells (NSCs) and neural progenitor cells (NPCs) are the subventricular zone (SVZ) of the lat...

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Detalhes bibliográficos
Main Authors: Aguirre, Adan, Rubio, Maria E., Gallo, Vittorio
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941915/
https://ncbi.nlm.nih.gov/pubmed/20844536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09347
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