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Facile Synthesis of Octahydrobenzo[h]isoquinolines: Novel and Highly Potent D(1) Dopamine Agonists

The octahydrobenzo[h]isoquinoline scaffold is of interest as a conformationally-restricted phenethylamine that may be useful for constructing biologically active products. Surprisingly, however, no tractable synthesis of this ring system has been reported. We now describe a facile method for obtaini...

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Bibliografiske detaljer
Main Authors: Bonner, Lisa A., Chemel, Benjamin R., Watts, Val J., Nichols, David E.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941879/
https://ncbi.nlm.nih.gov/pubmed/20709559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2010.07.052
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