P16(INK4a) MEDIATED SUPPRESSION OF TELOMERASE IN NORMAL AND MALIGNANT HUMAN BREAST CELLS

The cyclin-dependent kinase inhibitor p16(INK4a) (CDKN2A) is an important tumor-suppressor gene frequently inactivated in human tumors. p16 suppresses the development of cancer by triggering an irreversible arrest of cell proliferation termed cellular senescence. Here, we describe another anti-oncog...

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Bibliographic Details
Main Authors: Bazarov, Alexey V., van Sluis, Marjolein, Hines, Curtis, Bassett, Ekaterina, Beliveau, Alain, Campeau, Eric, Mukhopadhyay, Rituparna, Lee, Won Jae, Melodyev, Sonya, Zaslavsky, Yuri, Lee, Leonard, Rodier, Francis, Chicas, Agustin, Lowe, Scott W., Benhattar, Jean, Ren, Bing, Campisi, Judith, Yaswen, Paul
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941554/
https://ncbi.nlm.nih.gov/pubmed/20569236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2010.00599.x
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