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p53-dependent integration of telomere and growth factor deprivation signals
Ectopically expressed hTERT enables p16(INK4A)(−) human mammary epithelial cells to proliferate in the absence of growth factors, a finding that has led to the hypothesis that hTERT has growth regulatory properties independent of its role in telomere maintenance. We now show that telomerase can alte...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1838618/ https://ncbi.nlm.nih.gov/pubmed/17360541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700260104 |
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