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Hepatitis C Virus Core-Derived Peptides Inhibit Genotype 1b Viral Genome Replication via Interaction with DDX3X

The protein DDX3X is a DEAD-box RNA helicase that is essential for the hepatitis C virus (HCV) life cycle. The HCV core protein has been shown to bind to DDX3X both in vitro and in vivo. However, the specific interactions between these two proteins and the functional importance of these interactions...

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Détails bibliographiques
Auteurs principaux: Sun, Chaomin, Pager, Cara T., Luo, Guangxiang, Sarnow, Peter, Cate, Jamie H. D.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941470/
https://ncbi.nlm.nih.gov/pubmed/20862261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012826
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