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Hepatitis C Virus Core-Derived Peptides Inhibit Genotype 1b Viral Genome Replication via Interaction with DDX3X

The protein DDX3X is a DEAD-box RNA helicase that is essential for the hepatitis C virus (HCV) life cycle. The HCV core protein has been shown to bind to DDX3X both in vitro and in vivo. However, the specific interactions between these two proteins and the functional importance of these interactions...

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Detalhes bibliográficos
Main Authors: Sun, Chaomin, Pager, Cara T., Luo, Guangxiang, Sarnow, Peter, Cate, Jamie H. D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941470/
https://ncbi.nlm.nih.gov/pubmed/20862261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012826
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