Bone Is Not Essential for Osteoclast Activation

BACKGROUND: The mechanism whereby bone activates resorptive behavior in osteoclasts, the cells that resorb bone, is unknown. It is known that α(v)β(3) ligands are important, because blockade of α(v)β(3) receptor signaling inhibits bone resorption, but this might be through inhibition of adhesion or...

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Bibliographic Details
Main Authors: Fuller, Karen, Ross, Jade L., Szewczyk, Kinga A., Moss, Raymond, Chambers, Tim J.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941467/
https://ncbi.nlm.nih.gov/pubmed/20862258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012837
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