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Bone Is Not Essential for Osteoclast Activation

BACKGROUND: The mechanism whereby bone activates resorptive behavior in osteoclasts, the cells that resorb bone, is unknown. It is known that α(v)β(3) ligands are important, because blockade of α(v)β(3) receptor signaling inhibits bone resorption, but this might be through inhibition of adhesion or...

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Autors principals: Fuller, Karen, Ross, Jade L., Szewczyk, Kinga A., Moss, Raymond, Chambers, Tim J.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941467/
https://ncbi.nlm.nih.gov/pubmed/20862258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012837
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