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Theoretical Formulation of Principal Components Analysis to Detect and Correct for Population Stratification
The Eigenstrat method, based on principal components analysis (PCA), is commonly used both to quantify population relationships in population genetics and to correct for population stratification in genome-wide association studies. However, it can be difficult to make appropriate inference about pop...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2941459/ https://ncbi.nlm.nih.gov/pubmed/20862251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012510 |
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