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Tenuous paths in unexplored territory: From T cell receptor signaling to effector gene expression during thymocyte selection
During the last step of αβ T cell development, thymocytes that have rearranged genes encoding TCR chains and express CD4 and CD8 coreceptor are selected on the basis of their TCR reactivity to escape programmed cell death and become mature CD4 or CD8 T cells. This process is triggered by intrathymic...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2941441/ https://ncbi.nlm.nih.gov/pubmed/20537906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2010.04.013 |
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