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G-quadruplex structures in RNA stimulate mitochondrial transcription termination and primer formation

The human mitochondrial transcription machinery generates the primers required for initiation of leading-strand DNA replication. According to one model, the 3′ end of the primer is defined by transcription termination at conserved sequence block II (CSB II) in the mitochondrial DNA control region. W...

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Detalhes bibliográficos
Main Authors: Wanrooij, Paulina H., Uhler, Jay P., Simonsson, Tomas, Falkenberg, Maria, Gustafsson, Claes M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941323/
https://ncbi.nlm.nih.gov/pubmed/20798345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1006026107
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