Lanean...

Rapidly fatal myeloproliferative disorders in mice with deletion of Casitas B-cell lymphoma (Cbl) and Cbl-b in hematopoietic stem cells

Casitas B-cell lymphoma (Cbl)-family E3 ubiquitin ligases are negative regulators of tyrosine kinase signaling. Recent work has revealed a critical role of Cbl in the maintenance of hematopoietic stem cell (HSC) homeostasis, and mutations in CBL have been identified in myeloid malignancies. Here we...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Naramura, Mayumi, Nandwani, Neha, Gu, Hua, Band, Vimla, Band, Hamid
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941297/
https://ncbi.nlm.nih.gov/pubmed/20805496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1007575107
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!