Metabolic Profiling And The Metabolome-Wide Association Study: Significance Level For Biomarker Identification

High throughput metabolic profiling via the metabolome-wide association study (MWAS) is a powerful new approach to identify biomarkers of disease risk, but there are methodological challenges: high dimensionality, high level of collinearity, the existence of peak overlap within metabolic spectral da...

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Autori principali: Chadeau-Hyam, Marc, Ebbels, Timothy M D, Brown, Ian J, Chan, Queenie, Stamler, Jeremiah, Huang, Chiang Ching, Daviglus, Martha L, Ueshima, Hirotsugu, Zhao, Liancheng, Holmes, Elaine, Nicholson, Jeremy K, Elliott, Paul, De Iorio, Maria
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941198/
https://ncbi.nlm.nih.gov/pubmed/20701291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr1003449
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