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The LIM Protein Zyxin Binds CARP-1 and Promotes Apoptosis

Zyxin is a dual-function LIM domain protein that regulates actin dynamics in response to mechanical stress and shuttles between focal adhesions and the cell nucleus. Here we show that zyxin contributes to UV-induced apoptosis. Exposure of wild-type fibroblasts to UV-C irradiation results in apoptoti...

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Autors principals: Hervy, Martial, Hoffman, Laura M., Jensen, Christopher C., Smith, Mark, Beckerle, Mary C.
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publications 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941191/
https://ncbi.nlm.nih.gov/pubmed/20852740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601910376192
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