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Functional elucidation of a key contact between tRNA and the large ribosomal subunit rRNA during decoding

The selection of cognate tRNAs during translation is specified by a kinetic discrimination mechanism driven by distinct structural states of the ribosome. While the biochemical steps that drive the tRNA selection process have been carefully documented, it remains unclear how recognition of matched c...

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Autors principals: Ortiz-Meoz, Rodrigo F., Green, Rachel
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941108/
https://ncbi.nlm.nih.gov/pubmed/20739608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2232710
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