Molecular cloning, chromosomal localization, and functional characterization of a human liver Na+/bile acid cotransporter.

We have used a cDNA probe from a cloned rat liver Na+/taurocholate cotransporting polypeptide (Ntcp) to screen a human liver cDNA library. A 1,599-bp cDNA clone that encodes a human Na+/taurocholate cotransporting polypeptide (NTCP) was isolated. The human NTCP consists of 349 amino acids (calculate...

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Pubblicato in:	J Clin Invest
Autori principali:	Hagenbuch, B, Meier, P J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1994
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294097/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8132774/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117091
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