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Molecular cloning, chromosomal localization, and functional characterization of a human liver Na+/bile acid cotransporter.

We have used a cDNA probe from a cloned rat liver Na+/taurocholate cotransporting polypeptide (Ntcp) to screen a human liver cDNA library. A 1,599-bp cDNA clone that encodes a human Na+/taurocholate cotransporting polypeptide (NTCP) was isolated. The human NTCP consists of 349 amino acids (calculate...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Autores principales: Hagenbuch, B, Meier, P J
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 1994
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294097/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8132774/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117091
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