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A copper-lowering strategy attenuates amyloid pathology in a transgenic mouse model of Alzheimer’s disease
There is increasing evidence for the crucial role of metals in the pathology of Alzheimer’s disease. Both the aggregation and neurotoxicity of beta amyloid are dependent on the presence of copper. This study investigated the ability of the copper-complexing drug tetrathiomolybdate to reduce beta amy...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2940947/ https://ncbi.nlm.nih.gov/pubmed/20693639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2010-100408 |
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