Cyclosporin A inhibits CD40 ligand expression in T lymphocytes.

The ligand for CD40 is expressed on activated T lymphocytes and delivers contact-dependent activation signals to B lymphocytes. The mechanisms regulating CD40 ligand gene expression are largely unknown. Optimal expression of CD40 ligand required activation of protein kinase C and a rise in intracell...

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Pubblicato in:	J Clin Invest
Autori principali:	Fuleihan, R, Ramesh, N, Horner, A, Ahern, D, Belshaw, P J, Alberg, D G, Stamenkovic, I, Harmon, W, Geha, R S
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1994
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294093/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7907604/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117089
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