Cyclosporin A inhibits CD40 ligand expression in T lymphocytes.

The ligand for CD40 is expressed on activated T lymphocytes and delivers contact-dependent activation signals to B lymphocytes. The mechanisms regulating CD40 ligand gene expression are largely unknown. Optimal expression of CD40 ligand required activation of protein kinase C and a rise in intracell...

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Hlavní autoři: Fuleihan, R, Ramesh, N, Horner, A, Ahern, D, Belshaw, P J, Alberg, D G, Stamenkovic, I, Harmon, W, Geha, R S
Médium: Artigo
Jazyk:Inglês
Vydáno: 1994
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC294093/
https://ncbi.nlm.nih.gov/pubmed/7907604
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