Cyclosporin A inhibits CD40 ligand expression in T lymphocytes.
The ligand for CD40 is expressed on activated T lymphocytes and delivers contact-dependent activation signals to B lymphocytes. The mechanisms regulating CD40 ligand gene expression are largely unknown. Optimal expression of CD40 ligand required activation of protein kinase C and a rise in intracell...
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| Veröffentlicht in: | J Clin Invest |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
1994
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294093/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7907604/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117089 |
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