Homeostasis of the Naive CD4(+) T Cell Compartment during Aging

Despite thymic involution, the number of naive CD4(+) T cells diminishes slowly during aging, suggesting considerable peripheral homeostatic expansion of these cells. To investigate the mechanisms behind, and consequences of, naive CD4(+) T cell homeostasis, we evaluated the age-dependent dynamics o...

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Bibliographic Details
Main Authors: Kilpatrick, Ryan D., Rickabaugh, Tammy, Hultin, Lance E., Hultin, Patricia, Hausner, Mary Ann, Detels, Roger, Phair, John, Jamieson, Beth D.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940825/
https://ncbi.nlm.nih.gov/pubmed/18209045
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