Inhibitory effects on HAV IRES-mediated translation and replication by a combination of amantadine and interferon-alpha

Hepatitis A virus (HAV) causes acute hepatitis and sometimes leads to fulminant hepatitis. Amantadine is a tricyclic symmetric amine that inhibits the replication of many DNA and RNA viruses. Amantadine was reported to suppress HAV replication, and the efficacy of amantadine was exhibited in its inh...

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Detalhes bibliográficos
Main Authors: Yang, Lingli, Kiyohara, Tomoko, Kanda, Tatsuo, Imazeki, Fumio, Fujiwara, Keiichi, Gauss-Müller, Verena, Ishii, Koji, Wakita, Takaji, Yokosuka, Osamu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Short Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940810/
https://ncbi.nlm.nih.gov/pubmed/20815893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-7-212
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