Hepatic STAT1-Nuclear Translocation and Interleukin 28B Polymorphisms Predict Treatment Outcomes in Hepatitis C Virus Genotype 1-Infected Patients

BACKGROUND: We investigated associations between signal transducer and activator of transcription (STAT) 1 in pretreated liver tissues, interleukin (IL) 28B polymorphism and treatment response in hepatitis C virus (HCV)-infected patients treated with peginterferon and ribavirin. METHODS AND FINDINGS...

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Autors principals: Miyamura, Tatsuo, Kanda, Tatsuo, Nakamoto, Shingo, Wu, Shuang, Fujiwara, Keiichi, Imazeki, Fumio, Yokosuka, Osamu
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236206/
https://ncbi.nlm.nih.gov/pubmed/22174846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028617
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