Insulin-like growth factor-I and platelet-derived growth factor-BB induce directed migration of human arterial smooth muscle cells via signaling pathways that are distinct from those of proliferation.

Directed migration or chemotaxis of arterial smooth muscle cells (SMC) contributes to intimal SMC accumulation, a key event in the development of atherosclerotic lesions and in restenosis after angioplasty. The present study compares and contrasts insulin-like growth factor I (IGF-I) and platelet-de...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Bornfeldt, K E, Raines, E W, Nakano, T, Graves, L M, Krebs, E G, Ross, R
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1994
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294079/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8132765/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117081
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