Therapeutic potential of mesenchymal stem cells producing IFN-α in a mouse melanoma lung metastasis model

Adult stem cells represent a potential source for cell-based therapy of cancer. The present study evaluated the potential of bone marrow derived mesenchymal stem cells (MSC), genetically modified to express interferon (IFN)-α, for the treatment of lung metastasis in an immunocompetent mouse model of...

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Hlavní autoři: Ren, Changchun, Kumar, Sanjay, Chanda, Diptiman, Chen, Jian, Mountz, John D., Ponnazhagan, Selvarangan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940717/
https://ncbi.nlm.nih.gov/pubmed/18617688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/stemcells.2008-0084
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