Analysis of receptor tyrosine kinases (RTKs) and downstream pathways in chordomas(†)

We have previously demonstrated that chordomas express activated platelet-derived growth factor receptor (PDGFRB) and that treatment with imatinib, which is capable of switching off the activation of various receptor tyrosine kinases (RTKs) including PDGFRB, benefits a number of patients. The aim of...

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Hlavní autoři: Tamborini, Elena, Virdis, Emanuela, Negri, Tiziana, Orsenigo, Marta, Brich, Silvia, Conca, Elena, Gronchi, Alessandro, Stacchiotti, Silvia, Manenti, Giacomo, Casali, Paolo G., Pierotti, Marco A., Pilotti, Silvana
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2010
Témata:
Basic and Translational Investigations
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940683/
https://ncbi.nlm.nih.gov/pubmed/20164240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noq003
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