Phase III randomized trial of CED of IL13-PE38QQR vs Gliadel wafers for recurrent glioblastoma(†)

Convection-enhanced delivery (CED) of cintredekin besudotox (CB) was compared with Gliadel wafers (GW) in adult patients with glioblastoma multiforme (GBM) at first recurrence. Patients were randomized 2:1 to receive CB or GW. CB (0.5 µg/mL; total flow rate 0.75 mL/h) was administered over 96 hours...

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Detalhes bibliográficos
Main Authors: Kunwar, Sandeep, Chang, Susan, Westphal, Manfred, Vogelbaum, Michael, Sampson, John, Barnett, Gene, Shaffrey, Mark, Ram, Zvi, Piepmeier, Joseph, Prados, Michael, Croteau, David, Pedain, Christoph, Leland, Pamela, Husain, Syed R., Joshi, Bharat H., Puri, Raj K.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Clinical Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940677/
https://ncbi.nlm.nih.gov/pubmed/20511192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nop054
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