Chloroquine activates the p53 pathway and induces apoptosis in human glioma cells

Glioblastoma is the most common malignant brain tumor in adults. The currently available treatments offer only a palliative survival advantage and the need for effective treatments remains an urgent priority. Activation of the p53 growth suppression/apoptotic pathway is one of the promising strategi...

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Hlavní autoři: Kim, Ella L., Wüstenberg, Robin, Rübsam, Anne, Schmitz-Salue, Christoph, Warnecke, Gabriele, Bücker, Eva-Maria, Pettkus, Nadine, Speidel, Daniel, Rohde, Veit, Schulz-Schaeffer, Walter, Deppert, Wolfgang, Giese, Alf
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2010
Témata:
Basic and Translational Investigations
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940600/
https://ncbi.nlm.nih.gov/pubmed/20308316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nop046
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